Christian Ruff:Neurocomputational Underpinnings of Altered Mentalization in Autism

发布时间:2024-11-04浏览次数:10



活动安排

时间:2024117日(周四)13:30-15:00

讲座地点:松江校区2教楼235

主 讲 人:Christian Ruff  瑞士苏黎世大学经济系教授、社会与神经系统研究实验室(SNS-Lab)主任

主 持 人:沈强 ok138cn太阳集团 教授

讲座摘要:

A key behavioral characteristic of autistic people are difficulties with mentalization-understanding and reacting to the mental states of others. Despite their social and clinical implications, the specific neuro-cognitive mechanisms that may give rise to these difficulties have remained elusive. In my presentation, I will argue that one reason for this impasse may be limitations of the experimental approaches used to assess metalization. I will present a novel behavioral paradigm and computational model that can specifically assess adaptive mentalization. Using this paradigm and model in fMRI experiments, we have identified a multivariate neural fingerprint that can predict out of sample to what degree people can dynamically adapt their mental models of others to their changing strategies. We have also used this model and neural fingerprint in a preregistered study of autistic individuals, revealing that stronger autistic traits are associated with both a decreased ability for adaptive mentalization and weaker expression of the very same multivariate neural fingerprint. We hope that these results illustrate a specific deficit in adaptive mentalization that is linked to autistic traits.



嘉宾简介

Christian Ruff教授目前是苏黎世大学经济学系神经经济学与决策神经科学教授,社会与神经系统研究实验室(SNS-Lab)主任。英国伦敦大学学院认知神经科学博士学位,美国斯坦福大学访问学者。Ruff教授的研究领域高度跨学科,关注人类的行为动机、决策与学习,旨在开发能够解释和预测不同情境下选择和社会行为的计算模型。在SciencePNASNature NeuroscienceNature Human BehaviorNeuron国际顶尖期刊发表了多篇论文,并获得了欧洲研究委员Consolidator Grant等的经费资助


承办单位

营销科学系

科研与师资发展办公室



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